Sodium {[(3alpha,5beta,12alpha,20R)-3,12-dihydroxy-24-oxocholan-24-yl]amino}acetate(CAS: 16409-34-0)

Sodium {[(3alpha,5beta,12alpha,20R)-3,12-dihydroxy-24-oxocholan-24-yl]amino}acetate is a white crystalline solid with a high molecular weight. It has a low solubility in water but good solubility in organic solvents. The compound exhibits moderate reactivity towards bases and is stable under normal conditions. It is used in pharmaceutical applications requiring specific chemical reactivity.

Sodium {[(3alpha,5beta,12alpha,20R)-3,12-dihydroxy-24-oxocholan-24-yl]amino}acetate can be synthesized through a multi-step process involving the conversion of a cholic acid derivative to the corresponding amino acetate. Commonly, this involves protecting group chemistry, followed by deprotection and amidation steps to achieve high yield and selectivity. The reaction is typically performed under mild conditions to avoid degradation of the target compound.

Sodium {[(3alpha,5beta,12alpha,20R)-3,12-dihydroxy-24-oxocholan-24-yl]amino}acetate is primarily used in the pharmaceutical industry for the development of specific drug candidates. It is also relevant in the production of certain polymers and in the field of sensors for its unique chemical and biological properties.

When handling Sodium {[(3alpha,5beta,12alpha,20R)-3,12-dihydroxy-24-oxocholan-24-yl]amino}acetate, it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety glasses. The compound should be stored in a cool, dry place away from heat sources. In case of spill, it should be cleaned up using appropriate spill response materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.