Compound Q&A
How is 2',3'-O-Isopropylideneguanosine (CAS: 362-76-5) typically synthesized?
Answer
2',3'-O-Isopropylideneguanosine is synthesized through a multistep process starting from guanosine. Commonly, the synthesis involves protection of the 2' and 3' hydroxyl groups using isopropylidene acetic anhydride, followed by deprotection under basic conditions. The key steps include nucleophilic substitution and hydrolysis, with good yield and selectivity.
About
CAS No
362-76-5
English Name
2',3'-O-Isopropylideneguanosine
Molecular Formula
C13H17N5O5
Molecular Weight
323.31 g/mol
SMILES
CC1(OC2C(OC(C2O1)N3C=NC4=C3N=C(NC4=O)N)CO)C
InChIKey
XKPDAYWPKILAMO-IOSLPCCCSA-N
Last Updated: 2025-09-09 08:06
