Compound Q&A

How is 2-Chloro-5-methoxyaniline (CAS: 2401-24-3) typically synthesized?

Answer

2-Chloro-5-methoxyaniline
2-Chloro-5-methoxyaniline (CAS: 2401-24-3) can be synthesized through the reaction of 5-methoxyaniline with chlorine gas in the presence of a phase transfer catalyst, such as tetrabutylammonium bromide. The yield is typically around 80-85%, with the product isolated by recrystallization from suitable solvents.

About

CAS No 2401-24-3
English Name 2-Chloro-5-methoxyaniline
Molecular Formula C7H8ClNO
Molecular Weight 157.6 g/mol
SMILES COC1=CC(=C(C=C1)Cl)N
InChIKey GBOUQGUQUUPGLO-UHFFFAOYSA-N
Last Updated: 2025-09-09 08:06

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