Compound Q&A

How is 2-Bromo-1-(2-chlorophenyl)ethanone (CAS: 5000-66-8) typically synthesized?

Answer

2-Bromo-1-(2-chlorophenyl)ethanone
2-Bromo-1-(2-chlorophenyl)ethanone (CAS: 5000-66-8) is typically synthesized via a bromination reaction of 1-(2-chlorophenyl)ethanone with bromine in the presence of a catalyst such as iron(III) bromide. The reaction involves the introduction of a bromine atom at the alpha position of the ketone, yielding the desired compound with a yield of around 75-80%.

About

CAS No 5000-66-8
English Name 2-Bromo-1-(2-chlorophenyl)ethanone
Molecular Formula C8H6BrClO
Molecular Weight 233.49 g/mol
SMILES C1=CC=C(C(=C1)C(=O)CBr)Cl
InChIKey WZWWEVCLPKAQTA-UHFFFAOYSA-N
Last Updated: 2025-09-09 08:06

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