Compound Q&A

How is 1-(4-Piperidinyl)methanamine (CAS: 7144-05-0) typically synthesized?

Answer

1-(4-Piperidinyl)methanamine
1-(4-Piperidinyl)methanamine can be synthesized through a multi-step process involving amidation of 4-piperidone with methylamine. The reaction proceeds under basic conditions, and the use of a catalyst like triethylamine can enhance yield and selectivity. The final product is purified by recrystallization from a suitable solvent.

About

CAS No 7144-05-0
English Name 1-(4-Piperidinyl)methanamine
Molecular Formula C6H14N2
Molecular Weight 114.19200000000001 g/mol
SMILES C1CNCCC1CN
InChIKey LTEKQAPRXFBRNN-UHFFFAOYSA-N
Last Updated: 2025-09-09 08:06

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