Compound Q&A
How is 2-Bromo-1-fluoro-4-nitrobenzene (CAS: 701-45-1) typically synthesized?
Answer
2-Bromo-1-fluoro-4-nitrobenzene can be synthesized via bromination of 1-fluoro-4-nitrobenzene followed by bromination. Commonly, bromine in the presence of a Lewis acid like aluminum tribromide is used. The reaction is typically carried out under anhydrous conditions to prevent side reactions. The yield is usually around 75-80%, and the product can be purified by recrystallization.
About
CAS No
701-45-1
English Name
2-Bromo-1-fluoro-4-nitrobenzene
Molecular Formula
C6H3BrFNO2
Molecular Weight
220 g/mol
SMILES
C1=CC(=C(C=C1[N+](=O)[O-])Br)F
InChIKey
FAWMTDSAMOCUAR-UHFFFAOYSA-N
Last Updated: 2025-09-08 00:42
