Compound Q&A
How is (2E)-4-Ethoxy-4-oxo-2-butenoic acid (CAS: 2459-05-4) typically synthesized?
Answer
The synthesis of (2E)-4-Ethoxy-4-oxo-2-butenoic acid typically involves the reaction of ethyl acetoacetate with ethanol in the presence of a catalytic amount of a strong acid like sulfuric acid. The product is then purified by recrystallization from water. This method provides good yields and high purity. The reaction is exothermic, and care must be taken to control the temperature to prevent side reactions.
About
CAS No
2459-05-4
English Name
(2E)-4-Ethoxy-4-oxo-2-butenoic acid
Molecular Formula
C6H8O4
Molecular Weight
144.13 g/mol
SMILES
CCOC(=O)C=CC(=O)O
InChIKey
XLYMOEINVGRTEX-ONEGZZNKSA-N
Last Updated: 2025-09-08 00:42
