Compound Q&A

How is (2S)-Tetrahydro-2-furancarboxylic acid (CAS: 87392-07-2) typically synthesized?

Answer

(2S)-Tetrahydro-2-furancarboxylic acid
(2S)-Tetrahydro-2-furancarboxylic acid is typically synthesized by the reduction of 2,5-furandicarboxylic acid with sodium borohydride or lithium aluminum hydride. The reaction is carried out in anhydrous ether or tetrahydrofuran, with careful control of the reduction conditions to achieve the desired stereochemistry. The yield is generally high, and the method is scalable for industrial applications.

About

CAS No 87392-07-2
English Name (2S)-Tetrahydro-2-furancarboxylic acid
Molecular Formula C5H8O3
Molecular Weight 116.12 g/mol
SMILES OC(=O)[C@@H]1CCCO1
InChIKey UJJLJRQIPMGXEZ-BYPYZUCNSA-N
Last Updated: 2025-09-08 00:42

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