Compound Q&A

How is 3-Bromo-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-phenylalanine (CAS: 82278-73-7) typically synthesized?

Answer

3-Bromo-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-phenylalanine
3-Bromo-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-phenylalanine is synthesized by the bromination of N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-phenylalanine using N-bromosuccinimide (NBS) in the presence of a suitable organic solvent like dichloromethane. The reaction is carried out under UV light to enhance the bromination step. Yield and selectivity are key factors in the synthesis, with high purity achieved through recrystallization.

About

CAS No 82278-73-7
English Name 3-Bromo-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-phenylalanine
Molecular Formula C14H18BrNO4
Molecular Weight 344.20500000000004 g/mol
SMILES CC(C)(C)OC(=O)NC(CC1=CC(=CC=C1)Br)C(=O)O
InChIKey FBUDYESOPLBQIR-NSHDSACASA-N
Last Updated: 2025-09-08 00:42

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