Compound Q&A
How is (17beta)-3-Hydroxyestra-1,3,5(10)-trien-17-yl heptanoate (CAS: 4956-37-0) typically synthesized?
Answer
(17beta)-3-Hydroxyestra-1,3,5(10)-trien-17-yl heptanoate is typically synthesized via a multi-step process involving the esterification of 17beta-hydroxyestra-1,3,5(10)-trien-17-one with heptanoic acid. Commonly, a Lewis acid catalyst such as boron trifluoride etherate is used to promote the reaction, which yields a 90% selectivity and a 75% overall yield. The product is purified through recrystallization from ethanol.
About
CAS No
4956-37-0
English Name
(17beta)-3-Hydroxyestra-1,3,5(10)-trien-17-yl heptanoate
Molecular Formula
C25H36O3
Molecular Weight
384.56 g/mol
SMILES
CCCCCCC(=O)OC1CCC2C1(CCC3C2CCC4=C3C=CC(=C4)O)C
InChIKey
RFWTZQAOOLFXAY-BZDYCCQFSA-N
Last Updated: 2025-09-08 00:42
