Compound Q&A

How is (1-Hydroxy-2-(imidazo[1,2-a]pyridin-3-yl)ethane-1,1-diyl)diphosphonic acid (CAS: 180064-38-4) typically synthesized?

Answer

(1-Hydroxy-2-(imidazo[1,2-a]pyridin-3-yl)ethane-1,1-diyl)diphosphonic acid
(1-Hydroxy-2-(imidazo[1,2-a]pyridin-3-yl)ethane-1,1-diyl)diphosphonic acid is synthesized through a multi-step process involving the reaction of 1-hydroxy-2-(imidazo[1,2-a]pyridin-3-yl)ethane with phosphorus oxychloride or a similar reagent. The reaction is typically conducted under anhydrous conditions with the use of a suitable catalyst to enhance selectivity and yield. Detailed synthesis protocols can be found in the literature.

About

English Name (1-Hydroxy-2-(imidazo[1,2-a]pyridin-3-yl)ethane-1,1-diyl)diphosphonic acid
Molecular Formula C9H12N2O7P2
Molecular Weight 322.15 g/mol
SMILES C1=CC2=NC=C(N2C=C1)CC(O)(P(=O)(O)O)P(=O)(O)O
InChIKey VMMKGHQPQIEGSQ-UHFFFAOYSA-N
Last Updated: 2025-09-08 00:42

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