Compound Q&A
How is 8-Quinolinesulfonyl chloride (CAS: 18704-37-5) typically synthesized?
Answer
8-Quinolinesulfonyl chloride is typically synthesized by reacting 8-quinolinesulfonic acid with thionyl chloride. The reaction proceeds under anhydrous conditions to avoid hydrolysis, providing a high yield of the desired product with good selectivity. The process can be optimized with the use of a phase transfer catalyst to improve product purity and yield.
About
CAS No
18704-37-5
English Name
8-Quinolinesulfonyl chloride
Molecular Formula
C9H6ClNO2S
Molecular Weight
227.67 g/mol
SMILES
C1=CC2=C(C(=C1)S(=O)(=O)Cl)N=CC=C2
InChIKey
JUYUYCIJACTHMK-UHFFFAOYSA-N
Last Updated: 2025-09-08 00:42
