Compound Q&A
How is Dexamethasone sodium phosphate (CAS: 55203-24-2) typically synthesized?
Answer
Dexamethasone sodium phosphate is synthesized by first preparing dexamethasone acetate, which is then converted to the sodium phosphate salt. The synthesis involves several steps, including acetylation, reduction, and phosphonation. Common catalysts include sodium hydroxide and phosphoric acid. The overall process yields a product with high purity and selectivity, suitable for pharmaceutical applications.
About
CAS No
55203-24-2
English Name
Dexamethasone sodium phosphate
Molecular Formula
C22H28FNa2O8P
Molecular Weight
516.4 g/mol
SMILES
CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)COP(=O)([O-])[O-])O)C)O)F)C.[Na+].[Na+]
InChIKey
PLCQGRYPOISRTQ-FCJDYXGNSA-L
Last Updated: 2025-09-08 00:42
