Compound Q&A
How is Ethyl (2Z)-chloro(hydroxyimino)acetate (CAS: 14337-43-0) typically synthesized?
Answer
Ethyl (2Z)-chloro(hydroxyimino)acetate (CAS: 14337-43-0) is typically synthesized through the reaction of ethyl acetoacetate with hydroxylamine hydrochloride in the presence of a Lewis acid catalyst, such as boron trifluoride etherate. The reaction proceeds via a chlorocarbonyl intermediate, yielding a high yield of the desired product with good selectivity.
About
CAS No
14337-43-0
English Name
Ethyl (2Z)-chloro(hydroxyimino)acetate
Molecular Formula
C4H6ClNO3
Molecular Weight
151.55 g/mol
EINECS
604-347-4
SMILES
CCOC(=O)C(=NO)Cl
InChIKey
UXOLDCOJRAMLTQ-UTCJRWHESA-N
Last Updated: 2025-09-08 00:42