Compound Q&A

How is 1-(2-Chloro-3-pyridinyl)ethanone (CAS: 55676-21-6) typically synthesized?

Answer

1-(2-Chloro-3-pyridinyl)ethanone
1-(2-Chloro-3-pyridinyl)ethanone can be synthesized by a condensation reaction between 2-chloro-3-pyridinone and ethyl bromide in the presence of a base like sodium bicarbonate. The yield is around 70-80%, and the reaction is typically carried out in a solvent like methanol or ethanol. The product is isolated by filtration and recrystallization.

About

CAS No 55676-21-6
English Name 1-(2-Chloro-3-pyridinyl)ethanone
Molecular Formula C7H6ClNO
Molecular Weight 155.58 g/mol
SMILES CC(=O)C1=C(N=CC=C1)Cl
InChIKey WIWIOUAFBHZLNQ-UHFFFAOYSA-N
Last Updated: 2025-09-08 00:42

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