Compound Q&A

How is 2,2-Difluoroethanamine (CAS: 430-67-1) typically synthesized?

Answer

2,2-Difluoroethanamine
2,2-Difluoroethanamine (CAS: 430-67-1) is commonly synthesized via the reaction of 2,2-difluoroethanol with ammonium hydroxide. This process takes place in the presence of a suitable catalyst, such as palladium on carbon, and proceeds with good selectivity. The yield is typically around 80-90%, depending on the reaction conditions and purification method.

About

CAS No 430-67-1
English Name 2,2-Difluoroethanamine
Molecular Formula C2H5F2N
Molecular Weight 81.065 g/mol
SMILES C(C(F)F)N
InChIKey OVRWUZYZECPJOB-UHFFFAOYSA-N
Last Updated: 2025-09-08 00:42

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