How is (1S,3S,5R)-3-[(2-hydroxy-2,2-diphenylacetyl)oxy]-8lambda5-azaspiro[bicyclo[3.2.1]octane-8,1'-pyrrolidin]-8-ylium chloride (CAS: 10405-02-4) typically synthesized?

This compound can be synthesized via a multi-step process involving the formation of a key ester, followed by ring closure and subsequent cyclization. Commonly, a palladium-catalyzed coupling reaction is used for the formation of the ester, and the cyclization is achieved under platinum catalysis. Yield and selectivity are typically high, with careful control over reaction conditions.