Compound Q&A
How is 5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one (CAS: 1447-88-7) typically synthesized?
Answer
5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one (CAS: 1447-88-7) is typically synthesized via a multistep process involving the condensation of 4-hydroxyacetophenone with 2,4-dihydroxybenzaldehyde followed by methylation and subsequent chromone formation. This process often employs Lewis acids as catalysts, with yields around 70-80%. The reaction conditions include the use of solvents such as acetic acid and heating under reflux for extended periods.
About
CAS No
1447-88-7
English Name
5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one
Molecular Formula
C16H12O6
Molecular Weight
300.27 g/mol
SMILES
COC1=C(C2=C(C=C1O)OC(=CC2=O)C3=CC=C(C=C3)O)O
InChIKey
IHFBPDAQLQOCBX-UHFFFAOYSA-N
Last Updated: 2025-09-07 10:19
