Compound Q&A

How is 6-Methoxyquinoline (CAS: 5263-87-6) typically synthesized?

Answer

6-Methoxyquinoline
6-Methoxyquinoline is commonly synthesized via the methylation of 5-hydroxyquinoline. The reaction is catalyzed by phosphoric acid and typically proceeds with high yield and good selectivity. Other methods include the reduction of 7-chloro-6-methoxyquinoline with sodium borohydride, which gives the desired product with high purity.

About

CAS No 5263-87-6
English Name 6-Methoxyquinoline
Molecular Formula C10H9NO
Molecular Weight 159.19 g/mol
SMILES COC1=CC2=C(C=C1)N=CC=C2
InChIKey HFDLDPJYCIEXJP-UHFFFAOYSA-N
Last Updated: 2025-09-07 10:19

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