Compound Q&A

What are the physical and chemical properties of Linifanib (CAS: 796967-16-3)?

Answer

Linifanib
Linifanib (CAS: 796967-16-3) is a crystalline compound with a molecular weight of approximately 373.33 g/mol. It has a melting point of about 140°C and is sparingly soluble in water but soluble in organic solvents such as DMSO and methanol. Linifanib is a potent inhibitor of multiple receptor tyrosine kinases, including VEGFR, PDGFR, and FGFR. It is reactive towards electrophiles and can undergo hydrolysis under basic conditions.

About

English Name Linifanib
Molecular Formula C21H18FN5O
Molecular Weight 375.41 g/mol
SMILES CC1=CC(=C(C=C1)F)NC(=O)NC2=CC=C(C=C2)C3=C4C(=CC=C3)NN=C4N
InChIKey MPVGZUGXCQEXTM-UHFFFAOYSA-N
Last Updated: 2025-09-07 10:19

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