Compound Q&A
How is Besifloxacin HCl (CAS: 405165-61-9) typically synthesized?
Answer
Besifloxacin HCl is synthesized through a multi-step process that includes reactions such as alkylation, hydrogenation, and amidation. The key reagents and conditions include the use of hydrogen, borane in tetrahydrofuran (THF), and various solvents. The final step involves the addition of hydrochloric acid to form the hydrochloride salt. The overall yield is around 70-80%, with high selectivity towards the desired product.
About
CAS No
405165-61-9
English Name
Besifloxacin HCl
Molecular Formula
C19H22Cl2FN3O3
Molecular Weight
430.3070000000002 g/mol
SMILES
O=C(C1=CN(C2CC2)C3=C(C=C(F)C(N4C[C@H](N)CCCC4)=C3Cl)C1=O)O.[H]Cl
InChIKey
PMQBICKXAAKXAY-HNCPQSOCSA-N
Last Updated: 2025-09-07 10:19
