Compound Q&A

How is Trioctylphosphine oxide (CAS: 78-50-2) typically synthesized?

Answer

Trioctylphosphine oxide
Trioctylphosphine oxide (TOPO, CAS: 78-50-2) is synthesized by the reaction of trioctylphosphine with hydrogen peroxide in the presence of a base catalyst such as potassium hydroxide. The synthetic process involves careful control of pH and temperature to achieve high yield and selectivity. This method is widely used in the preparation of TOPO for various applications.

About

CAS No 78-50-2
English Name Trioctylphosphine oxide
Molecular Formula C24H51OP
Molecular Weight 386.6 g/mol
SMILES CCCCCCCCP(=O)(CCCCCCCC)CCCCCCCC
InChIKey ZMBHCYHQLYEYDV-UHFFFAOYSA-N
Last Updated: 2025-09-07 10:19

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