Compound Q&A
How is Methyl 3-(chlorosulfonyl)-2-thiophenecarboxylate (CAS: 59337-92-7) typically synthesized?
Answer
Methyl 3-(chlorosulfonyl)-2-thiophenecarboxylate (CAS: 59337-92-7) can be synthesized via the chlorosulfonation of 2-thiophenecarboxylic acid methyl ester using fuming sulfuric acid. The reaction proceeds under reflux conditions, and the yield can be improved by using a catalytic amount of a phase transfer catalyst. The product is then purified by recrystallization from a suitable solvent.
About
CAS No
59337-92-7
English Name
Methyl 3-(chlorosulfonyl)-2-thiophenecarboxylate
Molecular Formula
C6H5ClO4S2
Molecular Weight
240.69 g/mol
SMILES
COC(=O)C1=C(C=CS1)S(=O)(=O)Cl
InChIKey
PJVJBDAUWILEOG-UHFFFAOYSA-N
Last Updated: 2025-09-07 10:19
