Compound Q&A
How is 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS: 214360-73-3) typically synthesized?
Answer
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS: 214360-73-3) is synthesized by the boronic ester method, typically involving the reaction of an aryl halide or tosylate with a boronic acid in the presence of a base like sodium carbonate or potassium carbonate, and a palladium catalyst such as Pd(PPh3)2. The yield is usually high, around 80-90%.
About
CAS No
214360-73-3
English Name
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
Molecular Formula
C12H18BNO2
Molecular Weight
219.09 g/mol
SMILES
B1(OC(C(O1)(C)C)(C)C)C2=CC=C(C=C2)N
InChIKey
ZANPJXNYBVVNSD-UHFFFAOYSA-N
Last Updated: 2025-09-07 10:19
