Compound Q&A

How is 8-Methoxy-8-oxooctanoic acid (CAS: 3946-32-5) typically synthesized?

Answer

8-Methoxy-8-oxooctanoic acid
8-Methoxy-8-oxooctanoic acid (CAS: 3946-32-5) can be synthesized via the methylation of 8-oxooctanoic acid followed by the esterification of the resulting methyl ester with methanol in the presence of a strong acid catalyst like sulfuric acid. The yield is typically around 80-85%, and the selectivity towards the desired product is high.

About

CAS No 3946-32-5
English Name 8-Methoxy-8-oxooctanoic acid
Molecular Formula C9H16O4
Molecular Weight 188.22 g/mol
SMILES COC(=O)CCCCCCC(=O)O
InChIKey KOVPXZDUVJGGFU-UHFFFAOYSA-N
Last Updated: 2025-09-07 10:19

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