Compound Q&A
How is Triptorelin (CAS: 57773-63-4) typically synthesized?
Answer
Triptorelin is synthesized via solid-phase peptide synthesis (SPPS). Commonly, the reaction involves coupling of amino acids using Fmoc chemistry and protecting groups. The final step typically includes deprotection and cleavage from the resin using trifluoroacetic acid (TFA). The overall yield is around 50-70%, with high selectivity towards the desired product.
About
CAS No
57773-63-4
English Name
Triptorelin
Molecular Formula
C64H82N18O13
Molecular Weight
1311.47 g/mol
SMILES
CC(C)CC(C(=O)NC(CCCN=C(N)N)C(=O)N1CCCC1C(=O)NCC(=O)N)NC(=O)C(CC2=CNC3=CC=CC=C32)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(CO)NC(=O)C(CC5=CNC6=CC=CC=C65)NC(=O)C(CC7=CN=CN7)NC(=O)C8CCC(=O)N8
InChIKey
VXKHXGOKWPXYNA-PGBVPBMZSA-N
Last Updated: 2025-09-07 10:18
