Compound Q&A
How is 2,4-Difluorobiphenyl (CAS: 37847-52-2) typically synthesized?
Answer
2,4-Difluorobiphenyl (CAS: 37847-52-2) is typically synthesized via the coupling of 2-bromo-4-chlorobiphenyl with potassium fluoride in the presence of a base such as potassium carbonate. The reaction is performed under inert atmosphere to prevent side reactions. The yield is usually around 80%, and the product is purified by recrystallization to obtain the crystalline form.
About
CAS No
37847-52-2
English Name
2,4-Difluorobiphenyl
Molecular Formula
C12H8F2
Molecular Weight
190.19 g/mol
SMILES
C1=CC=C(C=C1)C2=C(C=C(C=C2)F)F
InChIKey
JVHAJKHGPDDEEU-UHFFFAOYSA-N
Last Updated: 2025-09-07 10:18
