Compound Q&A

How is Fmoc-Arg-OH (CAS: 91000-69-0) typically synthesized?

Answer

Fmoc-Arg-OH
Fmoc-Arg-OH is typically synthesized via the solid-phase peptide synthesis method. The key steps involve protecting the amino group with the Fmoc protecting group, followed by the stepwise addition of Arginine. Common solvents include dichloromethane and triethylamine. The overall yield is around 80-90%.

About

CAS No 91000-69-0
English Name Fmoc-Arg-OH
Molecular Formula C21H24N4O4
Molecular Weight 396.45 g/mol
SMILES C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CCCN=C(N)N)C(=O)O
InChIKey DVBUCBXGDWWXNY-SFHVURJKSA-N
Last Updated: 2025-09-07 10:18

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