Compound Q&A
How is 4-Amino-N-(4-methyl-2-pyrimidinyl)benzenesulfonamide (CAS: 127-79-7) typically synthesized?
Answer
4-Amino-N-(4-methyl-2-pyrimidinyl)benzenesulfonamide can be synthesized via the condensation of 4-methyl-2-pyrimidinamine with benzenesulfonyl chloride. The reaction is catalyzed by a strong acid, typically trifluoroacetic acid, in dichloromethane. The yield is typically 80-85%, and the product is obtained as a white solid.
About
CAS No
127-79-7
English Name
4-Amino-N-(4-methyl-2-pyrimidinyl)benzenesulfonamide
Molecular Formula
C11H12N4O2S
Molecular Weight
264.31 g/mol
SMILES
CC1=NC(=NC=C1)NS(=O)(=O)C2=CC=C(C=C2)N
InChIKey
QPPBRPIAZZHUNT-UHFFFAOYSA-N
Last Updated: 2025-09-07 10:18
