Compound Q&A

How is 5-Bromo-1H-indole-3-carbaldehyde (CAS: 877-03-2) typically synthesized?

Answer

5-Bromo-1H-indole-3-carbaldehyde
5-Bromo-1H-indole-3-carbaldehyde (CAS: 877-03-2) is commonly synthesized by bromination of 1H-indole-3-carbaldehyde using N-bromosuccinimide (NBS) as the brominating agent. The reaction is conducted in the presence of an organic solvent such as dichloromethane. High yields can be achieved under appropriate conditions, and the product can be purified by recrystallization from an appropriate solvent.

About

CAS No 877-03-2
English Name 5-Bromo-1H-indole-3-carbaldehyde
Molecular Formula C9H6BrNO
Molecular Weight 224.06 g/mol
SMILES Brc1ccc2[nH]cc(C=O)c2c1
InChIKey PEENKJZANBYXNB-UHFFFAOYSA-N
Last Updated: 2025-09-07 10:18

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