5-Bromo-1H-indole-3-carbaldehyde(CAS: 877-03-2)

5-Bromo-1H-indole-3-carbaldehyde (CAS: 877-03-2) is a crystalline solid with a molecular weight of approximately 224.04 g/mol. It is slightly soluble in water but miscible with common organic solvents like ethanol and acetone. The compound has a moderate reactivity, particularly in nucleophilic substitution reactions. It exhibits a strong absorption in the UV/Vis region, which can be used for spectroscopic analysis.

5-Bromo-1H-indole-3-carbaldehyde (CAS: 877-03-2) is commonly synthesized by bromination of 1H-indole-3-carbaldehyde using N-bromosuccinimide (NBS) as the brominating agent. The reaction is conducted in the presence of an organic solvent such as dichloromethane. High yields can be achieved under appropriate conditions, and the product can be purified by recrystallization from an appropriate solvent.

5-Bromo-1H-indole-3-carbaldehyde (CAS: 877-03-2) is used in the pharmaceutical industry for the synthesis of bioactive compounds. It also finds applications in the polymer industry as a precursor for the development of functional polymers. Additionally, it is utilized in the sensor industry for the preparation of gas sensors and in the semiconductor industry for the production of electronic materials.

5-Bromo-1H-indole-3-carbaldehyde (CAS: 877-03-2) should be handled with care in a well-ventilated area or under a fume hood. Protective equipment such as gloves, goggles, and a lab coat should be worn. Spills should be cleaned up immediately with appropriate solvent and disposed of according to local regulations. Always consult a safety data sheet (SDS) for detailed handling and storage instructions.