Compound Q&A

How is 2-Thiophenecarbonyl chloride (CAS: 5271-67-0) typically synthesized?

Answer

2-Thiophenecarbonyl chloride
2-Thiophenecarbonyl chloride can be synthesized by reacting thiophene with phosgene in the presence of a suitable catalyst, such as aluminum chloride. The reaction is exothermic and requires careful control of temperature to achieve high yield and selectivity. The product is typically purified by recrystallization or distillation.

About

CAS No 5271-67-0
English Name 2-Thiophenecarbonyl chloride
Molecular Formula C5H3ClOS
Molecular Weight 146.6 g/mol
SMILES C1=CSC(=C1)C(=O)Cl
InChIKey QIQITDHWZYEEPA-UHFFFAOYSA-N
Last Updated: 2025-09-07 10:18

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