Compound Q&A
How is 4-Bromo-2-fluorobenzonitrile (CAS: 105942-08-3) typically synthesized?
Answer
4-Bromo-2-fluorobenzonitrile (CAS: 105942-08-3) is commonly synthesized via a multi-step process, starting with 2-fluorobenzoic acid. The acid is nitrated to form 2-fluorobenzonitrile, which is then brominated. This synthesis often involves the use of concentrated sulfuric acid for nitration and N-bromosuccinimide for bromination, with high selectivity and good yields.
About
CAS No
105942-08-3
English Name
4-Bromo-2-fluorobenzonitrile
Molecular Formula
C7H3BrFN
Molecular Weight
189.03 g/mol
SMILES
C1=CC(=C(C=C1Br)F)C#N
InChIKey
HGXWRDPQFZKOLZ-UHFFFAOYSA-N
Last Updated: 2025-09-07 00:47
