Compound Q&A
What are the physical and chemical properties of Navitoclax (CAS: 923564-51-6)?
Answer
Navitoclax is a crystalline compound with a molecular weight of approximately 435.34 g/mol. It has a solubility of about 20 mg/mL in DMSO and is poorly soluble in water. Navitoclax is a potent inhibitor of BCL-2 family proteins, which makes it reactive towards these targets. It is stable under normal laboratory conditions but requires careful handling to maintain its activity.
About
CAS No
923564-51-6
English Name
Navitoclax
Molecular Formula
C47H55ClF3N5O6S3
Molecular Weight
974.63 g/mol
SMILES
CC1(CCC(=C(C1)CN2CCN(CC2)C3=CC=C(C=C3)C(=O)NS(=O)(=O)C4=CC(=C(C=C4)NC(CCN5CCOCC5)CSC6=CC=CC=C6)S(=O)(=O)C(F)(F)F)C7=CC=C(C=C7)Cl)C
InChIKey
JLYAXFNOILIKPP-KXQOOQHDSA-N
Last Updated: 2025-09-05 20:45
