Compound Q&A
How is 1-[4-(Trifluoromethoxy)phenyl]ethanone (CAS: 85013-98-5) typically synthesized?
Answer
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1-[4-(Trifluoromethoxy)phenyl]ethanone (CAS: 85013-98-5) is commonly synthesized via a Friedel-Crafts acylation reaction. The process involves the reaction of p-toluidine with trifluoromethoxyacetyl chloride in the presence of aluminum chloride as a catalyst. The reaction yields a high purity product with good selectivity and moderate to high yield.
About
CAS No
85013-98-5
English Name
1-[4-(Trifluoromethoxy)phenyl]ethanone
Molecular Formula
C9H7F3O2
Molecular Weight
204.14699999999993 g/mol
SMILES
CC(=O)c1ccc(cc1)OC(F)(F)F
InChIKey
MOEXTBIPPMLEFX-UHFFFAOYSA-N
Last Updated: 2025-09-05 16:09
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