Compound Q&A

What are the main uses of Lumacaftor (CAS: 936727-05-8)?

Answer

Lumacaftor
Lumacaftor is primarily used in combination with ivacaftor to treat cystic fibrosis in patients aged 12 years and older who have at least one F508del mutation in the CFTR gene. It helps to improve lung function and reduce hospital admissions.

About

English Name Lumacaftor
Molecular Formula C24H18F2N2O5
Molecular Weight 452.41 g/mol
SMILES CC1=C(N=C(C=C1)NC(=O)C2(CC2)C3=CC4=C(C=C3)OC(O4)(F)F)C5=CC(=CC=C5)C(=O)O
InChIKey UFSKUSARDNFIRC-UHFFFAOYSA-N
Last Updated: 2025-09-03 20:19

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