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Lumacaftor(CAS: 936727-05-8)
CAS Number
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Basic Information
Molecular Formula
C24H18F2N2O5
Molecular Weight
452.41 g/mol
Physical Properties
Boiling Point
653.013°C at 760 mmHg
Density
1.51
Chemical Identifiers
SMILES
CC1=C(N=C(C=C1)NC(=O)C2(CC2)C3=CC4=C(C=C3)OC(O4)(F)F)C5=CC(=CC=C5)C(=O)O
InChIKey
UFSKUSARDNFIRC-UHFFFAOYSA-N
Database References
MDL Number
MFCD16659051
FAQ
Lumacaftor is a drug used in the treatment of cystic fibrosis. Its molecular formula is C24H29NO2. It is a potent corrector of the ΔF508 mutation in cystic fibrosis transmembrane conductance regulator (CFTR) protein.
Lumacaftor is primarily used in combination with ivacaftor to treat cystic fibrosis in patients aged 12 years and older who have at least one F508del mutation in the CFTR gene. It helps to improve lung function and reduce hospital admissions.
Lumacaftor is generally considered safe when used as directed. Common side effects include headache, dizziness, and nasopharyngitis. It is important to follow dosage instructions and consult a healthcare provider for any concerns. Always handle the drug with gloves and avoid contact with eyes and skin.
Store Lumacaftor at 15°C to 25°C (59°F to 77°F) away from heat, moisture, and light. Keep the bottle tightly closed to prevent moisture absorption. Do not freeze. Use a child-proof container and store out of reach of children. Avoid exposure to extremes of temperature and humidity to ensure stability.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures
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