Compound Q&A

What is Lapatinib Impurity 9 (CAS: 231278-84-5)?

Answer

Lapatinib Impurity 9
Lapatinib Impurity 9, with the CAS number 231278-84-5, is a known byproduct or contaminant that may arise during the synthesis of lapatinib, a tyrosine kinase inhibitor used in cancer treatment. It typically has a molecular formula of C19H20N2O4S and is characterized by its structural similarity to the active compound, though it lacks the pharmacological activity. This impurity is often identified through analytical methods such as HPLC and mass spectrometry in pharmaceutical quality control.

About

English Name Lapatinib Impurity 9
Molecular Formula C26H17ClFN3O3
Molecular Weight 473.9 g/mol
SMILES C1=CC(=CC(=C1)F)COC2=C(C=C(C=C2)NC3=NC=NC4=C3C=C(C=C4)C5=CC=C(O5)C=O)Cl
InChIKey XQPZOUAAXRXPAM-UHFFFAOYSA-N
Last Updated: 2025-08-28 11:52

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