Compound Q&A

What is Tenofovir alafenamide hemifumarate (CAS: 1392275-56-7)?

Answer

Tenofovir alafenamide hemifumarate
Tenofovir alafenamide hemifumarate (CAS: 1392275-56-7) is an antiretroviral medication used to treat HIV infections. It is a prodrug form of tenofovir, designed to improve bioavailability and reduce systemic toxicity. The compound has a molecular formula of C14H21N6O15P and is characterized by its stability in solid form, solubility in water, and role as a nucleotide reverse transcriptase inhibitor (NRTI) in pharmaceutical applications.

About

English Name Tenofovir alafenamide hemifumarate
Molecular Formula C46H62N12O14P2
Molecular Weight 1069.02 g/mol
EINECS 805-448-8
SMILES CC(C)OC(=O)[C@H](C)N[P@](=O)(CO[C@H](C)Cn1cnc2c(N)ncnc12)Oc3ccccc3.CC(C)OC(=O)[C@H](C)N[P@](=O)(CO[C@H](C)Cn1cnc2c(N)ncnc12)Oc3ccccc3.OC(=O)/C=C/C(=O)O
InChIKey SVUJNSGGPUCLQZ-FQQAACOVSA-N
Last Updated: 2025-08-25 01:09

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