Compound Q&A

What are the main uses of Ponatinib (CAS: 943319-70-8)?

Answer

Ponatinib
Ponatinib is primarily used in oncology, particularly for the treatment of chronic myeloid leukemia (CML) and Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL). It is also being investigated for use in other cancers due to its broad kinase inhibitory activity.

About

English Name Ponatinib
Molecular Formula C29H27F3N6O
Molecular Weight 532.56 g/mol
SMILES CC1=C(C=C(C=C1)C(=O)NC2=CC(=C(C=C2)CN3CCN(CC3)C)C(F)(F)F)C#CC4=CN=C5N4N=CC=C5
InChIKey PHXJVRSECIGDHY-UHFFFAOYSA-N
Last Updated: 2025-08-25 01:08

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