Compound Q&A

What are the main uses of Trimethylsilyl trifluoromethanesulfonate (CAS: 27607-77-8)?

Answer

Trimethylsilyl trifluoromethanesulfonate
Trimethylsilyl trifluoromethanesulfonate (TMSOTf) is widely used in pharmaceuticals for drug synthesis, in industrial processes as a catalyst, and in research for functional group transformations. It also serves as a protecting group reagent in organic chemistry and is applied in the production of specialty chemicals and materials due to its reactivity and stability.

About

CAS No 27607-77-8
English Name Trimethylsilyl trifluoromethanesulfonate
Molecular Formula C4H9F3O3SSi
Molecular Weight 222.25999999999993 g/mol
EINECS 248-565-4
SMILES C[Si](C)(C)OS(=O)(=O)C(F)(F)F
InChIKey FTVLMFQEYACZNP-UHFFFAOYSA-N
Last Updated: 2025-08-25 01:07

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