Compound Q&A

What is Trimethylsilyl trifluoromethanesulfonate (CAS: 27607-77-8)?

Answer

Trimethylsilyl trifluoromethanesulfonate
Trimethylsilyl trifluoromethanesulfonate, also known as TMSOTf, is an organosilicon compound with the chemical formula (CH3)3SiO·CF3SO2. It is a colorless liquid with a sharp odor, commonly used as a catalyst and reagent in organic synthesis. TMSOTf is known for its strong Lewis acidity and is often employed in reactions involving silanes and sulfonates.

About

CAS No 27607-77-8
English Name Trimethylsilyl trifluoromethanesulfonate
Molecular Formula C4H9F3O3SSi
Molecular Weight 222.26 g/mol
EINECS 248-565-4
SMILES C[Si](C)(C)OS(=O)(=O)C(F)(F)F
InChIKey FTVLMFQEYACZNP-UHFFFAOYSA-N
Last Updated: 2025-08-25 01:07

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