(+-)-Bay K 8644(CAS: 71145-03-4)

Methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydro-3-pyridinecarboxylate has a crystalline form with a molecular weight of approximately 429.3 g/mol. It is sparingly soluble in water but soluble in organic solvents like methanol and ethanol. The compound is chemically stable but reactive towards reducing agents. It has a characteristic melting point around 160-165°C.

Methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydro-3-pyridinecarboxylate is synthesized via a multi-step process involving the reaction of 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]pyridine with acetic anhydride. The reaction is catalyzed by an acid, typically sulfuric acid, under reflux conditions. The yield is around 85%, and the product is purified by recrystallization.

Methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydro-3-pyridinecarboxylate is used in the pharmaceutical industry for the synthesis of various drug molecules. It is also utilized in the chemical industry for the development of new materials and in the production of sensors and semiconductors due to its unique chemical structure.

When handling Methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydro-3-pyridinecarboxylate, it is essential to use personal protective equipment (PPE) including gloves, goggles, and a lab coat. The compound should be stored in a fume hood to minimize exposure. In case of a spill, it should be contained and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions.