(R)-(-)-IBUPROFEN(CAS: 51146-57-7)

(2R)-2-(4-Isobutylphenyl)propanoic acid has a crystalline form and a molecular weight of approximately 222.32 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol. The compound is moderately reactive, particularly towards nucleophilic substitution reactions. Its melting point is around 58-60°C.

(2R)-2-(4-Isobutylphenyl)propanoic acid is synthesized via a multi-step process, usually involving the protection of the carboxylic acid group, followed by substitution reactions. Common methods include Wittig reactions or Grignard reagents, with high selectivity and moderate yield. Specific catalysts and reagents are chosen based on the reaction conditions and desired product purity.

(2R)-2-(4-Isobutylphenyl)propanoic acid is used in the pharmaceutical industry for the synthesis of certain drugs, in polymer manufacturing as a functional monomer, and in the electronics industry for sensor applications. Its unique chemical properties make it suitable for various specialized applications.

When handling (2R)-2-(4-Isobutylphenyl)propanoic acid, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate methods, and the site should be decontaminated. Always refer to the Safety Data Sheet (SDS) for detailed instructions and emergency procedures.