( R ) -PIPERAZINE-2-CARBOXYLIC ACID(CAS: 31321-68-3)

(2R)-2-Piperazinecarboxylic acid is a white crystalline solid with a molecular weight of approximately 135.14 g/mol. It has a pKa of about 6.2 and is slightly soluble in water. This compound is known for its basic nature and is reactive towards acids, forming salts. It is often used in chemical synthesis and research due to its unique structure.

(2R)-2-Piperazinecarboxylic acid is synthesized from 2-amino-2-piperidinecarboxylic acid through a process involving hydrogenation or via a condensation reaction with appropriate reagents. Commonly, this acid is produced in multi-step syntheses with good yields and reproducibility, often requiring suitable catalysts and reaction conditions to achieve high purity.

(2R)-2-Piperazinecarboxylic acid is widely used in the pharmaceutical industry for the development of drug intermediates and in polymer chemistry for the synthesis of functional polymers. It is also utilized in sensor technology and semiconductor manufacturing due to its unique chemical properties.

When handling (2R)-2-Piperazinecarboxylic acid, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and storage information.