( 1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXAMIDE(CAS: 112794-29-3)

1,2,3,4-Tetrahydro-3-isoquinolinecarboxamide (CAS: 112794-29-3) is a colorless to white crystalline solid with a molecular weight of 218.24 g/mol. It has a solubility of 3.6 g/L in water. Chemically, it is soluble in methanol and ethanol but less soluble in water. It is reactive in acidic conditions and has a pKa of approximately 7. It is stable under normal storage conditions but should be handled with care due to potential hydrolysis under acidic conditions.

1,2,3,4-Tetrahydro-3-isoquinolinecarboxamide (CAS: 112794-29-3) can be synthesized via a condensation reaction between 3-isoquinolinecarboxylic acid and an appropriate primary amine. Commonly, this is achieved using a carbodiimide as a coupling agent under basic conditions. The yield is typically around 85-90%, with good selectivity. This method ensures a high-quality product suitable for various applications.

1,2,3,4-Tetrahydro-3-isoquinolinecarboxamide (CAS: 112794-29-3) is primarily used in the pharmaceutical industry for the development of certain drugs. It also has applications in the polymer industry for enhancing material properties. Additionally, it is used in the sensor industry for detecting specific chemical compounds and in semiconductors for improving material quality.

When handling 1,2,3,4-Tetrahydro-3-isoquinolinecarboxamide (CAS: 112794-29-3), it is important to use proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be performed in a well-ventilated area or a fume hood to minimize exposure. Ensure that all spills are contained and cleaned up immediately using appropriate materials. Refer to the Safety Data Sheet (SDS) for detailed handling and disposal procedures.