7-Bromo-1-methyl-1H-indole(CAS: 280752-68-3)

7-Bromo-1-methyl-1H-indole is a crystalline compound with a molecular weight of approximately 230.04 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and dichloromethane. The compound is moderately reactive, especially under basic conditions. It is stable under normal storage conditions but should be protected from light and moisture.

7-Bromo-1-methyl-1H-indole is typically synthesized via the bromination of 1-methylindole using N-bromosuccinimide (NBS) as the brominating agent. The reaction is carried out in a solvent such as dichloromethane. The yield is usually around 70-80%, and the selectivity is good, leading to the brominated product with high purity.

7-Bromo-1-methyl-1H-indole is used in the pharmaceutical industry for the synthesis of certain bioactive compounds. It is also explored in the sensor industry for its potential as a selective and sensitive detection material. Additionally, it has potential applications in the polymer industry for the development of new materials with specific properties.

When handling 7-Bromo-1-methyl-1H-indole, it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be handled with caution using appropriate absorbents. Always refer to the Safety Data Sheet (SDS) for detailed emergency protocols and storage recommendations.