N-{[(2-Methyl-2-propanyl)oxy]carbonyl}alanine(CAS: 3744-87-4)

N-{[(2-Methyl-2-propanyl)oxy]carbonyl}alanine (CAS: 3744-87-4) is a white crystalline powder. Its molecular weight is approximately 262.37 g/mol. This compound has a slight solubility in water and is practically insoluble in organic solvents. It exhibits moderate acidity and can undergo condensation reactions with nucleophiles. It is stable under normal storage conditions but should be kept away from strong bases and oxidizing agents.

N-{[(2-Methyl-2-propanyl)oxy]carbonyl}alanine (CAS: 3744-87-4) is synthesized through a multistep process involving the protection of the carboxyl group of alanine, followed by the introduction of the 2-methyl-2-propanol moiety via an esterification reaction. Commonly, a catalyst such as HOBt (1-Hydroxybenzotriazole) is used to improve the reaction selectivity. The overall process yields a high purity product with good yield.

N-{[(2-Methyl-2-propanyl)oxy]carbonyl}alanine (CAS: 3744-87-4) is primarily used in the pharmaceutical industry for the synthesis of certain peptides and prodrugs. It is also utilized in the polymer industry for the modification of polymer chains, and in the sensor industry for specific chemical and biological detection applications. Its use in semiconductors is less common but can be applied in some specialized areas.

When handling N-{[(2-Methyl-2-propanyl)oxy]carbonyl}alanine (CAS: 3744-87-4), it is essential to wear appropriate personal protective equipment (PPE), such as gloves and safety goggles. The substance should be handled in a well-ventilated area or a fume hood. In case of a spill, use absorbent material and dispose of the waste according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal information.