Compound Q&A

How is N-{[(2-Methyl-2-propanyl)oxy]carbonyl}alanine (CAS: 3744-87-4) typically synthesized?

Answer

N-{[(2-Methyl-2-propanyl)oxy]carbonyl}alanine
N-{[(2-Methyl-2-propanyl)oxy]carbonyl}alanine (CAS: 3744-87-4) is synthesized through a multistep process involving the protection of the carboxyl group of alanine, followed by the introduction of the 2-methyl-2-propanol moiety via an esterification reaction. Commonly, a catalyst such as HOBt (1-Hydroxybenzotriazole) is used to improve the reaction selectivity. The overall process yields a high purity product with good yield.

About

CAS No 3744-87-4
English Name N-{[(2-Methyl-2-propanyl)oxy]carbonyl}alanine
Molecular Formula C8H15NO4
Molecular Weight 189.21 g/mol
SMILES CC(NC(=O)OC(C)(C)C)C(=O)O
InChIKey QVHJQCGUWFKTSE-UHFFFAOYSA-N
Last Updated: 2025-09-09 19:18

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