(2S)-2-Oxetanylmethanol(CAS: 2090778-00-8)

(2S)-2-Oxetanylmethanol is a colorless liquid with a distinctive odor. Its molecular weight is approximately 108.12 g/mol. The compound is poorly soluble in water but soluble in common organic solvents like ethanol and acetone. It has a pKa of around 15.6, indicating basic properties. The compound is reactive towards nucleophiles and can form esters and amides under the right conditions.

(2S)-2-Oxetanylmethanol can be synthesized via a reduction of (2S)-2-oxetanone using sodium borohydride or lithium aluminum hydride as the reducing agent. The reaction is typically carried out in an ether solvent like diethyl ether. High yield and good selectivity are achieved under mild conditions, making it a practical method for laboratory and industrial synthesis.

(2S)-2-Oxetanylmethanol finds applications in various industries. In pharmaceuticals, it serves as a building block for the synthesis of certain APIs. It is also used in the production of polymers, particularly in the modification of polyurethane systems. Additionally, the compound is utilized in sensor technology, contributing to the development of gas detection devices. Its use in semiconductor manufacturing is also emerging, where it serves as a precursor in the formation of organic semiconductors.

When handling (2S)-2-Oxetanylmethanol, it is crucial to use appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. If spills occur, they should be promptly cleaned up using absorbent materials, and the area should be well-ventilated. In case of skin contact or inhalation, seek medical attention immediately. Refer to the Safety Data Sheet (SDS) for detailed emergency procedures and storage instructions.